Ingenuity pathways analysis summary. To investigate possible interactions of differently regulated genes, datasets representing 568 genes with altered expression profile obtained from the RNAseq data for HP-PRRSV rJXwn06 were imported into the Ingenuity Pathway Analysis Tool and the following data is illustrated: The network representation of the most highly rated network (Gene Expression, Cell Death, Lipid Metabolism). The genes that are shaded were determined to be significant from the statistical analysis. The genes shaded red are up-regulated and those that are green are down-regulated. The intensity of the shading shows to what degree each gene was up or down-regulated. A solid line represents a direct interaction between the two gene products and a dotted line means there is an indirect interaction. Genes associated with Cell Death are circled with orange color.
Miller et al. BMC Veterinary Research 2012 8:208 doi:10.1186/1746-6148-8-208