Table 8

Effect of analgesic treatment on gait kinetics measured using a force-plate
Kinetic parameters ABT-116 (n = 12) Carprofen (n = 11) Tramadol (n = 9) Placebo (n = 9)
Peak Vertical Force 4.4 ± 6.8 1.2 ± 7.5 2.1 ± 4.9 2.8 ± 10.6
Statistical Power 0.07 0.07 0.05
Sample Size for Power > 0.8 485 445 >1000
Peak Vertical Impulse 2.3 ± 13.4 2.4 ± 7.1 −1.1 ± 6.9 −1.8 ± 6.9
Statistical Power 0.14 0.24 0.05
Sample Size for Power > 0.8 100 45 >1000
Falling Slope −3.2 ± 19.0 −0.6 ± 16.2 4.6 ± 19.5a 11.1 ± 35.2a
Statistical Power 0.10 0.14 0.08
Sample Size for Power > 0.8 185 95 275

Note: Data represent percentage change in Week 3 of the trial, when compared with mean baseline. Power analysis results compare each treatment group with placebo. aFalling slope is more negative after treatment (undesirable effect).

Malek et al.

Malek et al. BMC Veterinary Research 2012 8:185   doi:10.1186/1746-6148-8-185

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