Table 8 |
||||
| Effect of analgesic treatment on gait kinetics measured using a force-plate | ||||
| Kinetic parameters | ABT-116 (n = 12) | Carprofen (n = 11) | Tramadol (n = 9) | Placebo (n = 9) |
| Peak Vertical Force | 4.4 ± 6.8 | 1.2 ± 7.5 | 2.1 ± 4.9 | 2.8 ± 10.6 |
| Statistical Power | 0.07 | 0.07 | 0.05 | |
| Sample Size for Power > 0.8 | 485 | 445 | >1000 | |
| Peak Vertical Impulse | 2.3 ± 13.4 | 2.4 ± 7.1 | −1.1 ± 6.9 | −1.8 ± 6.9 |
| Statistical Power | 0.14 | 0.24 | 0.05 | |
| Sample Size for Power > 0.8 | 100 | 45 | >1000 | |
| Falling Slope | −3.2 ± 19.0 | −0.6 ± 16.2 | 4.6 ± 19.5a | 11.1 ± 35.2a |
| Statistical Power | 0.10 | 0.14 | 0.08 | |
| Sample Size for Power > 0.8 | 185 | 95 | 275 | |
Note: Data represent percentage change in Week 3 of the trial, when compared with mean baseline. Power analysis results compare each treatment group with placebo. aFalling slope is more negative after treatment (undesirable effect).
Malek et al. BMC Veterinary Research 2012 8:185 doi:10.1186/1746-6148-8-185
