Table 5

Genes involved in over-manifested cellular pathways in macrophages grown as a co-culture with canine mammary cancer cells

Pathway

number of genes

P-value


Angiogenesis

13

1.17E-04


p53 pathway feedback loops 2

6

2.16E-04


Wnt signaling pathway

17

2.90E-04


Alzheimer disease-presenilin pathway

9

1.04E-03


Cadherin signaling pathway

9

1.55E-03


p53 pathway

8

1.63E-03


Plasminogen activating cascade

3

2.84E-03


TGF-beta signaling pathway

8

5.07E-03


Inflammation mediated by chemokine and cytokine signaling pathway

12

9.09E-03


Arginine biosynthesis

2

1.29E-02


Alzheimer disease-amyloid secretase pathway

5

1.77E-02


Alpha adrenergic receptor signaling pathway

3

2.68E-02


Metabotropic glutamate receptor group I pathway

3

3.95E-02


FGF signaling pathway

6

4.05E-02


Succinate to proprionate conversion

1

4.16E-02


PLP biosynthesis

1

4.16E-02


Endothelin signaling pathway

5

4.29E-02


Muscarinic acetylcholine receptor 1 and 3 signaling pathway

4

4.67E-02


The list of over-manifested cellular PANTHER pathways in macrophages grown as co-cultures with canine mammary cancer cells. The binomial test for each PANTHER pathway was used

Król et al. BMC Veterinary Research 2012 8:16   doi:10.1186/1746-6148-8-16

Open Data