Figure 8.

Invasion of canine mammary cancer cell lines and growth characteristics in Matrigel matrix. (A) The graph of fluorescence intensity related to invasion of canine mammary cancer cell lines (CMT-U27, CMT-U309, P114, CMT-W1 and CMT-W2) grown as a mono-culture (ctrl) and as a co-culture with macrophages (+MQ). The statistical analysis was performed using Prism version 5.00 software (GraphPad Software, USA). The unpaired t-test was applied to analyze the results. p < 0.05 was regarded as significant and marked as * whereas p < 0.001 was regarded as highly significant and marked as ***. (B) Pictures of highly invaded CMT-W1 and CMT-W2 cells (green fluorescence) obtained using Olympus BX60 microscope examined in control conditions and after co-culturing with macrophages. (C) Growth characteristics of CMT-U27, CMT-U309, P114, CMT-W1 and CMT-W2 cell lines (phase contrast micrographs) grown on Matrigel matrix for 24 hrs.

Król et al. BMC Veterinary Research 2012 8:16   doi:10.1186/1746-6148-8-16
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