Table 3

Genes belonging to the heat shock protein family whose expression levels were the most correlated with initial or overall tenderness scores in the reference group (young bulls slaughtered year 1)
Correlation with initial tenderness Correlation with overall tenderness
Animal type Year Number of animals Person coefficient Spearman coefficient Person coefficient Spearman coefficient
Hsp27* young bulls year 1 25 -0.53 -0.50 -0.51 -0.50
DNAJA1 young bulls year 1 25 -0.50 -0.59 -0.48 -0.59
DNAJC3 young bulls year 1 25 -0.48 -0.49 -0.40 -0.49
HspH1 young bulls year 1 25 -0.47 -0.47 -0.43 -0.47
HspA8 young bulls year 1 25 -0.46 -0.50 -0.44 -0.50
HspB1 young bulls year 1 25 -0.46 -0.43 -0.42 -0.42
DNAJB5 young bulls year 1 25 -0.42 -0.45 -0.39 -0.49
HspA6 young bulls year 1 25 -0.41 -0.40 -0.42 -0.37
CRYAB young bulls year 1 25 -0.40 -0.38 -0.40 -0.41

Among the 70 genes belonging to the heat shock protein family with probes on the GENOTEND chip, some genes were identified with the highest correlation coefficients with tenderness scores (they were the most associated with tenderness through the principal component analysis). Individual correlation coefficients (Pearson coefficient and Spearman coefficient) are indicated for each gene. Standard errors on the estimates of Pearson coefficients are between 0.18 and 0.19. Multiple regression analyses were performed with the combination of the first 6 genes (bold type) for young bulls slaughtered year 1. All together, these 6 genes explained up to 49-50% of the total variability in tenderness in the reference group.

*Probes for Hsp27 were determined on the basis of previously published proteomic studies whereas probes for other genes were determined on the basis of previous transciptomic studies.

Hocquette et al.

Hocquette et al. BMC Veterinary Research 2012 8:135   doi:10.1186/1746-6148-8-135

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