Table 4

Effect of weaning induced stress on the relative gene expression of IL-1ß, IL-2, IL-4, IL-8, IFN-γ, TNFα and lymphotoxin in weaned beef calves.

Gender

Location

s.e.

Time

s.e.

P-Values




Variable

Male

Female

Near

Away

0

1

3

7

G

L

T

I




IL-1β

17.7

16.2

16.6

17.3

1.3

8.7

18.5c

18.5c

21.9c

1.7

NS

NS

***

NS

IL-2

9.9

10.8

11.8

8.9

1.9

9.6

12.6

10.1

9.2

1.8

NS

NS

NS

*1

IL-4

11.8

11.9

13.6

10.1

1.8

11.5

15.3

10.5

10.2

1.8

NS

NS

NS

NS

IL-8

7.1

11.5

8.9

9.7

1.3

5.6

12.9c

9.2a

9.7

1.8

*

NS

**

NS

IFN-γ

19.4

36.8

29.3

26.8

5.8

14.2

41.4c

30.5b

26.2b

5.7

*

NS

***

*2

TNFα

3.0

3.7

3.5

3.3

0.22

2.4

3.8c

3.4b

3.8c

0.29

*

NS

***

*3

Lymphotoxin

78.6

104.1

100.3

82.4

11.9

96.1

100.6

82.1

86.5

10.2

NS

NS

NS

NS


The values are expressed as least squares means (Lsmeans) and s.e.

G = gender, L = location, T = time, I = interaction, NS = not significant (P > 0.05). * = P < 0.05, ** = P < 0.01, *** = P < 0.001.

a, b, cWithin rows, Lsmeans differ from pre-weaning baseline by P < 0.05, P < 0.01 and P < 0.001, respectively.

1Gender × Time interaction, 9.3 vs 9.8, 10.9 vs 14.4, 11.8 vs 8.4, 7.6 vs 10.8 for male and female calves at time 0, 1, 3 and 7, respectively.

2Gender × Time interaction, 9.0 vs 19.4, 22.2 vs 60.6, 26.7 vs 34.3, 19.6 vs 31.7 for male and female calves at time 0, 1, 3 and 7, respectively.

3Gender × Time interaction, 2.4 vs 2.4, 3.0 vs 4.6, 3.5 vs 3.2, 3.1 vs 4.4 for male and female calves at time 0, 1, 3 and 7, respectively.

O'Loughlin et al. BMC Veterinary Research 2011 7:45   doi:10.1186/1746-6148-7-45

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