Table 6

Relative frequency of clinical signs at observations over time post inoculation compared to control cattle

Study

1

1

1

1

2

2

2


Groups

100 g

1 g

1 g

100 g

4

3

2


Postmortem BSE diagnosis

Pos

Pos

Neg

Neg

Pos

Neg

Neg


Behaviour


Flank licking

↑↑↑

↑↑

↓↓↓

↓↓↓

↓↓↓


Unusual asymmetrical ear movements

↑↑↑

↑↑


Vocalisation

↑↑


Head toss

↑↑


Snorting

↑↑

↓↓↓


Nose licking

↑↑

↓↓↓


Grooming self

↑↑

↑↑


Apprehension

↑↑

↑↑↑


BSE series of events

↓↓↓

↑↑


Grooming others

↑↑

↑↑


Standing idle & not approached

↓↓↓

↓↓↓

↑↑↑


Mounting

↑↑

↑↑↑

↑↑

↑↑↑


Sneezing

↑↑


Being mounted


Head rubbing

↓↓↓


Nose wrinkling

↓↓↓


Coughing

↓↓↓


Sensation


Startle at movement including hand approach/clipboard test

↑↑↑

↑↑↑

↑↑↑


Hyperaesthesia

↑↑↑

↓↓

↑↑↑


Startle at movement

↑↑↑

↑↑↑

↑↑↑


Startle at noise

↑↑

↑↑↑


Abnormal hand approach/clipboard test

↑↑


Movement and posture


Muscle fasciculations

↑↑

↑↑↑

↑↑


Tremor

↑↑


Abnormal head carriage


Groups were compared with undosed controls (study 1) and saline-inoculated controls (study 2).

↑= greater/↓ = lower hazard rate than controls, with P<0.001 (three arrows), P = 0.001-0.01 (two arrows) and P>0.01 and <0.0125 (four comparisons) or <0.0167 (three comparisons) (one arrow). Blank cell: no significant difference.

Only signs that were significantly differently displayed compared to controls are listed.

Konold et al. BMC Veterinary Research 2010 6:53   doi:10.1186/1746-6148-6-53

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