Additional file 7.
138 (BSE negative-HP&IHC). Steer, examined prior to cull at 42 months after oral dosing with 100 g of BSE brainstem homogenate (study 1). The steer's behaviour during cranial nerve testing is unremarkable. It appears apprehensive in the corridor, particularly on approaching the channel and drain and the hose across the floor. Trembling of the rump muscles is visible from behind when the animal stops in front of the channel before crossing it. Note also the mild startle when the examiner walks in front of the steer whilst it is exploring the channel. This steer was negative for BSE by postmortem tests upon examination of the brain. In a separate study, PrPd was found in the lymphoid follicles of the ileum of this steer, which suggests that it was infected with the BSE agent (GAH Wells and M Stack, unpublished observation).
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Konold et al. BMC Veterinary Research 2010 6:53 doi:10.1186/1746-6148-6-53