Table 2

SNPs identified in AKR1C genes genotyped in 1/4 Meishan F8 and F10 population.

Allele frequencies3


Assay

Gene

Accession1

Location2

Polymorphism

F8 & F10

MS

WC

Polymorphic site4


33391_261 C/T

AKR1CL2

BV102614

Intron 1

T = 0.63

T = 0.21

T = 0.81

ccctgcacagYagcgcgggca

49422_42 A/T

AKR1C2

BV680531

nt 179

Ile16Phe

A = 0.77

A = 0.50

A = 1.00

cggtcacctcWttcctgtact

36962_196 A/T

AKR1C2

DQ474066

nt 779

Tyr216Asn

A = 0.62

A = 0.17

A = 0.89

tttggttgccWatgctgccct

36962_681 A/G

AKR1C2

DQ474066

nt 833

Val234 Ile

G = 0.85

ND

ND

aaaccacccaRttctcttgg

31063_1495 G/T

AKR1C4

BV680526

promoter

ERE site

T = 0.55

T = 0.10

T = 0.94

tcagagtactKaccttgacca

31503_2415 A/G

AKR1C4

BV680525

Exon 1

silent

G = 0.81

G = 1.00

G = 0.67

tgagtagtggRgaagagacgt

27648_208 C/T

AKR1C4

BV680527

Exon 1

silent

T = 0.67

T = 0.36

T = 0.86

agctgaatgaYgggcacctca

20502_681 C/T

AKR1C4

BV680537

Intron 2

C = 0.57

C = 0.17

C = 0.92

cttttagctaYtgatgtttmc

20502_722 C/T

AKR1C4

BV680537

Intron 2

C = 0.78

C = 0.50

C = 1.00

aaatcayaagYcatttttaat

14984_99 G/T

AKR1C4

BV680523

Intron 4

T = 0.56

ND

ND

aaatgtgggtKtgatccctgg

36969_772 C/T

AKR1C4

BV680543

Exon 7

silent

C = 0.56

C = 0.25

C = 0.94

agaaacacaaYagaagcccag

49431_198 C/T

AKR1C4

BV680533

Intron 8

Splice site

T = 0.58

T = 0.50

T = 0.81

ttcccttcctYycaggtttttr


1Accession numbers beginning with BV are sequences submitted to dbSTS.

2Location refers to nucleotide position in cDNA.

3Allele frequencies were calculated from F8 and F10 animals genotyped (ranging from 238–420 animals), and founder Meishan (MS) and founder White composite (WC) animals (7–10 animals each) in the original resource population; ND = not determined.

4Polymorphisms are identified by IUB code with flanking genomic sequence.

Nonneman et al. BMC Veterinary Research 2006 2:28   doi:10.1186/1746-6148-2-28

Open Data