Table 1

Peruvian Paso horses affected with DSLD

age, sex
 onset of symptoms
 clinical
 family affected
 legs
 patella
 heart
 PA
 aorta
 eyes
 other tissues
 ultrasound
1
 1 y, M
 6 mos
 four
 sire
 4 mod
 ND
 cor +
 ND
 +
 both+
 nuchal+
 2/2 front SLs
2
 1 y, F
 6 mos
 four
 sire
 4 mild
 ND
 cor +
 ND
 +
 -
 nuchal, lung +
 2/2 front SLs
3
 18 mo M
 6 mos
 four
 parents
 4 mild
 ND
 ND
 ND
 ND
 ND
 nuchal+
 ND
4
 18 mo M
 6 mos
 four
 parents
 4 mod
 ND
 ND
 ND
 ND
 ND
 nuchal+
 ND
5
 1.5 y, M
 at 1 y
 four
 dam
 4 mild
 +
 -
 +
 -
 both+
 lung +
 4 SLs
6
 2 y, F
 birth
 four
 sire
 4 mod
 ND
 ND
 ND
 +
 ND
 ND
 ¾ SLs
7
 3 y, F
 6 mos
 rear
 parents
 4 mild
 +
 cor +
 ND
 +
 both +
 nuchal, lung +
 4 SLs
8
 3 y, M
 1 year
 front legs
 no
 4 severe
 ND
 cor +
 ND
 +
 ND
 nuchal+
 ND
9
 7 y, F
 years
 four
 dam
 4 severe
 ND
 valve+
 +
 +
 ND
 lung +
 2/4 SLs
10
 8 y, M
 years
 four
 sire, foals
 1 SL exam, mod*
 ND
 ND
 ND
 ND
 L eye +
 nuchal+
 4 SLs
11
 9 y, F
 at 9 y
 rear
 dam
 4 severe
 ND
 valve+
 +
 +
 ND
 lung +
 4 SLs
12
 9 y, M
 at 6 y
 four
 no
 4 mild
 +
 cor +
 +
 +
 both+
 -
 4 SLs
13
 9 y, M
 years
 fallen crest, legs
 dam
 4 mild
 ND
 cor +
 ND
 -
 both +
 nuchal, lung +
 ND
14
 11 y, F
 years
 four
 no
 1 SL exam, mild*
 ND
 ND
 ND
 ND
 R eye +
 nuchal+
 2/2 hind SLs
15
 15 y, F
 years
 four
 no
 4 mod
 ND
 ND
 ND
 +
 ND
 ND
 4 SLs
16
 15 y, F
 years
 front
 foal
 4 mod
 +
 cor +
 PA+
 +
 both +
 nuchal+
 ND
17
 15 y, F
 years
 four
 sire, son
 4 mod
 ND
 cor +
 ND
 +
 both +
 nuchal, shoulder+
 ND
18
 18 y, F
 years
 four
 no
 1 leg exam, severe*
 ND
 ND
 ND
 ND
 ND
 ND
 4 SLs
19
 18 y, F
 years
 rear legs
 foals
 4 mild
 ND
 ND
 ND
 -
 R eye +
 nuchal, lung +
 4 SLs
20
 21 y, M
 late onset
 four
 no
 4 mod
 +
 cor +
 -
 -
 R eye +
 -
 4 SLs
21
 21 y, M
 years
 legs
 no
 4 severe
 ND
 cor +
 ND
 +
 R eye +
 lung +
 4 SLs
22
 unknown
 unknown
 unknown
 no
 4 mild
 ND
 -
 ND
 -
 ND
 -
 ND

Age: age at necropsy; ND: not done; legs: SDFT, DDFT and SL; cor: coronary artery; PA: pulmonary artery; nuchal: nuchal ligament

Mild, mod (moderate), severe: describes the average severity of pathology in examined leg tendons and ligaments; +: accumulation of proteoglycans in other tissues; -: no proteoglycan accumulation

*only limited tissue was available for examination

Halper et al. BMC Veterinary Research 2006 2:12   doi:10.1186/1746-6148-2-12