The expression of marker genes for adipogenesis (A), chondrogenesis (B), and osteogenesis (C). Compared to control cells, these marker genes in both hACL-SCs and hMCL-SCs were highly upregulated when the ligament stem cells were grown in the respective induction media. The RT-PCR results were obtained from a 29-year-old female donor (see Table 1). The results from another two donors were similar (not shown). ALP, alkaline phosphatase; Coll. II, collagen type II; Cont., control; Differ., differentiated; LPL, lipoprotein lipase;.
Zhang et al. BMC Medicine 2011 9:68 doi:10.1186/1741-7015-9-68