Table 2

Final analysis

Hypothesis

1. Does the hypothesis take into account the key pathological findings?

2. Is the hypothesis congruent with the key epidemiological risk factors?

3. Does the hypothesis link 1 and 2?


Brainstem control of respiratory function

No

No

No

Brainstem control of cardiac function

Partly

Yes

Partly

Respiratory obstruction/unintentional asphyxia

No

Partly

No

Common bacterial toxins

Yes

Yes

Yes

Shock including anaphylaxis

Yes

Yes

Partly

Thermal stress

Partly

Yes

No

Diaphragm failure

Partly

Yes

Partly

CO2 rebreathing

No

No

No

toxic gases emitted from fungally colonized mattresses

No

No

No

Abuse

No

No

No


Goldwater BMC Medicine 2011 9:64   doi:10.1186/1741-7015-9-64

Open Data