Table 4

Outputs of all three models using standardized set of input parameters for hypothetical countries in the subA-Saharan African (SSA) region, Southeast Asian (SEA) region and Latin America and the Caribbean (LAC) region

Hypothetical country, SSA region

Hypothetical country, SEA region

Hypothetical country, LAC region


Results

ADIP

Pan-American Health Organization (PAHO) TriVac

SUPR

ADIP

PAHO TriVac

SUPR

ADIP

PAHO TriVac

SUPR


D

S

D/S

D

S

D

S

D/S

D

S

D

S

D/S

D

S


Outcomes:


Life years gained

5,657

1,228

18,500a

1,511

1,781

109,405

22,584

295,344a

1,511

2,228

17,568

7,648

99,204a

1,511

3,847


Death averted

-

-

567a

18

30

-

-

8,786a

18

32

-

-

2,924a

18

53


QALYs gained

-

-

2,438

3,523

-

-

-

2,438

4,123

-

-

-

2,438

5,474


DALYs averted

5,681

1,254

18,950a

-

-

109,839

23,084

301,953a

-

-

17,640

7,761

100,736a

-

-


Costs (US$):


Incremental cost per live birth population

-74,020

4,863,640

72,796,429

61,454,589

-36,736,421

84,234,567

83,385,318

1,025,138,030

61,454,589

40,278,151

-540,048

10,300,512

160,611,146

61,454,589

-28,181,083


Incremental cost per person

-1.23

80

60

84

-607

90

89

55

84

43

-3.85

73

57

84

-201


Incremental cost-effectiveness ratio (US$):


Incremental cost per DALYs averted

-

3,878

3,842

-

-

767

3,612

3,395

-

-

-

1,327

1,594

-

-


Incremental cost per life year gained

-

3,961

3,935

40,683

-

770

3,692

3,471

40,683

18,081

-

1,347

1,619

40,683

-


Incremental cost per death averted

-

127,290

-

-

-

25,763

123,289

-

-

-

-

45,206

-

-

-


Incremental cost per case averted

-

-

1,348

-

-

-

1,311

-

-

-

-

1,324

-

-


Incremental cost per hospitalization averted

-

-

9,278

-

-

-

-

10,706

-

-

-

-

9,047

-

-


Incremental cost per death averted

-

-

128,397

3,336,028

-

-

-

116,673

3,336,028

1,276,894

-

-

54,935

3,336,028

-


Incremental cost per QALYs

-

-

-

25,210

-

-

-

-

25,210

9,770

-

-

-

25,210

-


Default means the outputs using the predefined model inputs. Standardized means the outputs using the standardized model input.

aPer 20 cohorts.

ADIP = Pneumo ADIP; SUPR = Supremes; D = default; S = standardized

Chaiyakunapruk et al. BMC Medicine 2011 9:53   doi:10.1186/1741-7015-9-53

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