Table 2

Input values for standardized analysis in each hypothetical country in the sub-Saharan African (SSA) region, Southeast Asian (SEA) region and Latin America and the Caribbean (LAC) region

Model parameters

Standardized values


SSA region

SEA region

LAC region


Population:


Total number of birth per year

60,477

932,115

140,414


Life expectancy at birth (in years)

59.45

70.62

72.9


Burden of disease:


Incidence of pneumococcal pneumonia (per 100,000 per year)

1,793

1,793

1,771


Incidence of meningitis (per 100,000 per year)

10

10

18


Incidence of invasive NPNM (per 100,000 per year)

77

77

137


Incidence of otitis media (per 100,000 per year)

400

400

400


Case fatality rate of pneumococcal pneumonia

1

1

1.8


Case fatality rate of pneumococcal meningitis

20

20

36.8


Case fatality rate of invasive NPNM

10

10

20.46


Vaccine information:


Vaccine coverage*

89%

97%

83%


Serotype coverage of pneumococcal pneumonia

60%

60%

60%


Vaccine efficacy of pneumococcal pneumonia

97.40%

97.40%

97.40%


Vaccine efficacy of pneumococcal meningitis

97.40%

97.40%

97.40%


Vaccine efficacy of pneumococcal invasive NPNM

97.40%

97.40%

97.40%


Vaccine efficacy of otitis media

57%

57%

57%


Costing information:


Dose cost

$26.35

$26.35

$26.35


Standardized input of vaccine cost (US$26.35) = £16.096 (rate US$1 = £0.61) (from http://www.xe.com/ucc/ webcite) [1-3].

NPNM = non-pneumonia non-meningitis.

Chaiyakunapruk et al. BMC Medicine 2011 9:53   doi:10.1186/1741-7015-9-53

Open Data