Table 2

Antibiotic prescription at initial visit (and within 48 hours of initial visit) for adult patients with acute respiratory tract infection, according to randomisation group (rapid result vs. delayed result)

Antibiotic prescription

Rapid result (n = 202)

Delayed result (n = 204)

P


Initial antibiotic treatment, n (%)

9 (4.5)

25 (12.3)

0.005a

At initial visit

7 (3.5)

21 (10.3)

After 24 to 48 hours

2 (1.0)

4 (2.0)

β-lactamb

4 (2.0)

13 (6.4)

-

Tetracycline

4 (2.0)

8 (3.9)

-

Macrolide

1 (0.5)

3 (1.5)

-

Quinolone

-

1 (0.5)

-

Patient demographics at initial antibiotic treatment, n (%)

Body temperature ≥38.5°C, n (%)

-

4 (33.3c)

-

CRP level ≥50 mg/L, n (%)

2 (8.3d)

10 (67.0e)

< 0.001a

Duration of illness ≤5 days, n (%)

3 (3.3f)

12 (12.4f)

0.02a

Duration of illness > 5 days, n (%)

6 (5.4)

13 (12.1)

-

Patients with virus detected, n (%)

91 (45.0)

91 (44.6)

-

Antibiotics prescribed

3 (3.3g)

11 (12.1g)

0.03a

Patients with Mycoplasma pneumoniae detected, n (%)

5 (2.5)

2 (1.0)

-

Antibiotics prescribed, n

2h

2h

Patients with Chlamydophila pneumoniae detected, n (%)

1 (0.5)

-

Antibiotics prescribed, n

1i

-

-


aχ2 test; bphenoxymethylpenicillin or amoxicillin with or without clavulanic acid or loracarbef; cfour (33.3%) of twelve patients; dtwo (8.3%) of twenty-four patients; e10 (67.0%) of 15 patients; fthree (3.3%) of ninety-one patients and 12 (12.4%) of 97 patients, respectively; gthree (3.3%) of ninety-one patients and 11 (12.1%) of 91 patients, respectively; hone patient received antibiotics within 24 hours and the other within 48 hours in each group, for a total of two patients in each group as indicated in table; ipatient received antibiotics within 48 hours.

Brittain-Long et al. BMC Medicine 2011 9:44   doi:10.1186/1741-7015-9-44

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