Table 1

Important properties of mucoid and nonmucoid phenotypes of Pseudomonas aeruginos a in the respiratory tract of cystic fibrosis patientsa

Property

Mucoid phenotype

Nonmucoid phenotype


Location in the lungs

Respiratory zone and conductive zone in sputum

Conductive zone in sputum

Biofilm formation in vitro

Yes

Yes

Biofilm formation in vivo

Yes

No

Multiply antibiotic resistance due to conventional mechanisms

Seldom

Frequent

Resistance (tolerance) due to biofilm properties

Yes

No

Responsible for lung tissue damage

Yes

No

Induces pronounced antibody response

Yes

No


aTable 1 is based on data in references [9] and [10].

Høiby BMC Medicine 2011 9:32   doi:10.1186/1741-7015-9-32

Open Data