Table 1 |
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Important properties of mucoid and nonmucoid phenotypes of Pseudomonas aeruginos a in the respiratory tract of cystic fibrosis patientsa |
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Property |
Mucoid phenotype |
Nonmucoid phenotype |
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Location in the lungs |
Respiratory zone and conductive zone in sputum |
Conductive zone in sputum |
|
Biofilm formation in vitro |
Yes |
Yes |
|
Biofilm formation in vivo |
Yes |
No |
|
Multiply antibiotic resistance due to conventional mechanisms |
Seldom |
Frequent |
|
Resistance (tolerance) due to biofilm properties |
Yes |
No |
|
Responsible for lung tissue damage |
Yes |
No |
|
Induces pronounced antibody response |
Yes |
No |
|
|
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Høiby BMC Medicine 2011 9:32 doi:10.1186/1741-7015-9-32 |
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