Table 1

Characteristics of included studies

First author, study year [reference]

Number of patients

Age

(years)

Gender

n

Appendicitis prevalence (%)

Country

Setting

Study type

Patient population


Abdeldaim 2007 [19]

242

Median 42

Range 8 to 76

Male 90

Female 152

51

Ireland

Emergency department

Retrospective

Right iliac fossa pain

Al Qahtani 2004 [8]

211

Mean 32

Range 13 to 70

Male 125

Female 86

57

Saudi Arabia

Emergency department

Prospective

Suspected acute appendicitis

Alvarado 1986 [5]

277

Mean 25.3

Range 4 to 80

Male 131

Female 96

82

USA

Hospital inpatients

Prospective

Abdominal pain

Arain 2001 [20]

100

Mean 19.9

Males 44

Females 56

48

Pakistan

Surgical unit

Prospective

Suspected acute appendicitis

Baidya 2007 [44]

231

Mean 26.3

Range 16 to 65

Male 141

Female 90

52

India

Emergency department

Prospective

Right iliac fossa pain

Bond 1990 [21]

187

Range 0 to 18

61

USA

Emergency department

Prospective

Abdominal pain

Borges 2003 [22]

76

Age 2 to 6 = 23 Age 7 to 10 = 38 Age > 10 = 15

Male 40

Female 36

71

Brazil

Emergency department

Prospective

Suspected acute appendicitis

Canavosso 2008 [23]

224

Mean 26.65

Range 13 to 82

Male 117

Female 10

84

Argentina

Emergency department

Prospective

Right lower quadrant pain

Chan 2001 [25]

148

Mean 29

Range 10 to 73

Male 107

Female 41

34

Singapore

Emergency department

Retrospective

Suspected acute appendicitis

Chan 2003 [24]

175

Mean 30

Range 8 to 73

Male 130

Female 45

43

Singapore

Emergency department

Prospective

Right iliac fossa pain

Denizbasi 2003 [45]

221

Mean 26.6

Male 112

Female 109

79

Turkey

Emergency department

Prospective

Abdominal pain and suspected acute appendicitis

Escriba 2011 [42]

99

Mean 11.2

Range 4 to 17.8

Male 62

Female 37

42

Spain

Emergency department

Prospective

Abdominal pain/suspected appendicitis

Farahnak 2007 [26]

21

-

-

48

Iran

Emergency department

Prospective

Abdominal pain

Gwynn 2001 [27]

215

-

-

66

USA

Emergency department

Retrospective

Abdominal pain

Hsiao 2005 [28]

222

Mean 9.4

Range 1 to 13

Male 146

Female 76

50

Taiwan

Emergency department

Retrospective

Suspected acute appendicitis

Kang 1989 [46]

62

Mean 45.8

Range 18 to 78

Male 42

Female

68

China

Hospital inpatients

Prospective

Suspected acute appendicitis

Khan 2005 [29]

100

Mean 20.2

Range 9 to 56

Female 59

Male 41

54

Pakistan

Surgical ward

Prospective

Suspected acute appendicitis

Kim 2006 [9]

211

-

-

83

Korea

Surgical ward

Retrospective

Suspected acute appendicitis

Kim 2008 [18]

157

Mean 37.1

Range 15 to 84

-

57

Korea

Emergency department

Prospective observational study

Abdominal pain

Lada 2005 [10]

83

Mean 27.5

Range 15 to 75

Male 43

Female 40

88

Argentina

Emergency department

Prospective

Suspected acute appendicitis

Malik 2000 [56]

100

Mean 22

Range 14 to 18

Male 81

Female 19

92

Pakistan

Surgical unit

Prospective

Suspected acute appendicitis

McKay 2007 [31]

150

Mean 34

Range 18 to 76

Male 78

Female 65

32

USA

Emergency department

Retrospective

Abdominal pain

Memon 2009 [32]

100

Mean age 24

Range 13 to 55

Male 65

Female 35

91

Pakistan

Surgical Ward

Prospective study

Suspected acute appendicitis

Muenzer 2010 [47]

28

Test Cohort Mean 11

Validation cohort

Mean 11

Range 2 to 17

Test cohort Male 10

Female 10

Validation cohort

Male 4

Female 4

54

USA

Emergency department

Unclear

Abdominal pain

Owen 1992 [11]

215

Male 75

Female 70

Children 70

58

Wales

Emergency department

Prospective observational study

GP referral for

Suspected acute appendicitis

Petrosyan 2008 [33]

1,630

Male:

Median 29 yrs

Range 3 to 85 yrs

Female:

Median 34 yrs

Range 2 to 86 yrs

Male 928

Female 702

54

USA

Emergency department

Retrospective

Right lower quadrant pain and suspected acute appendicitis

Rezak 2011 [40]

59

Mean 8.5

Range 3 to 16

Male 43

Female 16

51

USA

Community teaching hospital

Retrospective

Suspected appendicitis

Saidi 2000 [43]

128

Male 49

Female 79

35

Iran

Emergency department

Prospective

Suspected acute appendicitis

Sanabria 2007 [34]

374

Mean 29.5

Range 15 to 71

Male 178

Female 196

55

Columbia

Emergency department

Prospective

Right iliac fossa pain and

suspected acute appendicitis

Schneider 2007 [12]

588

Median 11.9

Range 3 to 21

33

USA

Emergency department

Prospective cohort

Suspected acute appendicitis

Shreef 2010 [41]

350

Mean 9.3

Range 8 to 14

Male 228

Female 122

38

Egypt, Saudi Arabia

Emergency department

Prospective

Suspected acute appendicitis

Shrivastava 2004 [57]

100

Male 45

Female 30

78

India

Emergency department

Prospective

Suspected acute appendicitis

Singh 2008 [35]

100

Mean 22.6 Median 25

Male 55

Female 45

62

India

Surgical Ward

Prospective

Suspected acute appendicitis

Soomro 2008 [36]

227

Mean 20.47

Range 10 to 62

Male 150

Females 77

55

Pakistan

Emergency department

Prospective

Suspected acute appendicitis

Stephens 1999 [37]

94

Mean 44

Range 3 to 79

Males 46

Female 48

89

USA

Surgical unit

Retrospective

All patients who underwent

appendectomy for

suspected acute appendicitis

Tade 2007 [38]

100

Range 17 to 56

Males 63

Female 37

34

Nigeria

Emergency department

Prospective

Right iliac fossa pain and suspected acute appendicitis

Wani 2007 [30]

96

Mean 25.46

Range 7 to 70

Male 48

Female 48

70

India

Surgical unit

Prospective

Suspected acute appendicitis

Yildirim 2008 [39]

143

Mean 34

Range 18 to 76

Male 78

Females 65

85

Turkey

Emergency department

Prospective study

Abdominal pain

Winn 2004 [58]

142

39

Australia

Surgical ward

Retrospective

Suspected acute appendicitis

Subotic 2008 [59]

57

Mean 27.5

Range 16 to 70

Male 27

Female 30

84

Serbia

Emergency department

Prospective

Suspected acute appendicitis

Andersson 2008 [60]

229

Mean 23

Males 105

Females 124

33

Sweden

Emergency department

Prospective

Suspected acute appendicitis

Prabhudesai 2008 [61]

60

Mean 25.4

Male 27

Female 33

40

UK

Emergency department

Prospective

Suspected acute appendicitis


Ohle et al. BMC Medicine 2011 9:139   doi:10.1186/1741-7015-9-139

Open Data