Additional file 1.

Figure S1. Summary ROC curves (sensitivity and specificity with 95% CIs are presented in Table 2). Figure S2. Predicted versus observed cases with appendicitis per study, sub-grouped by prevalence. The studies were re-grouped into high- or low-prevalence according to the prevalence cut-off point (82%) found in Alvarado's derivation study: A. Low risk, score 1 to 4; B. Intermediate risk, score 5 to 6; C. High risk, score 7 to 10.

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Ohle et al. BMC Medicine 2011 9:139   doi:10.1186/1741-7015-9-139