Pathway analysis of the lymphocte-specific gene (A) or urine peptide (B) markers. Data mining software (Ingenuity Systems, http://www.ingenuity.com webcite, Redwood City, CA) was used with differentially (KD vs FC) expressed genes or peptides to identify gene ontology groups and relevant canonical signaling pathways. The intensity of the node color indicates the degree of up- (red) or down- (green) regulation in KD. Nodes are displayed using shapes that represent the functional classes of the gene products, and different line types represent various relationships. Relationships are primarily due to co-expression. Abbreviations: FC, febrile controls; KD, Kawasaki disease.
Ling et al. BMC Medicine 2011 9:130 doi:10.1186/1741-7015-9-130