Table 7

Additional SNPs identified using the relaxed filter.

SNP

Disease(s)

Characterized genes in duplicons


rs10147986

CD

(40 duplicons)

rs10502407

BD

[CIDEA]

rs10896468

CAD

OR8U8, OR5M8

rs11010995

RA

-

rs11028186

RA

ALG1L, ASNS, [ZNF195], [FAM86B2], [DEFB10P1], [DEFA5], [ZFYVE20]

rs11053044

T2D

ALG10, ALG10B

rs11118278

CAD

CR1L, MCP

rs1192923

HT

[ORAOV1]

rs12227938

BD, CAD, T1D

ALG10, ALG10B

rs12256867

T2D

ZNF33A, ZNF37A, ZNF33B, ZNF37B, [ZNF25]

rs12413153

CAD

DDX18, BTBD15, WDR22, [IBRDC2]

rs1291361

BD

HTR7, HTR7P, [HEBP1]

rs1404223

CAD

-

rs17080801

T2D

PARP4, TPTE2

rs17230081

T2D

ORM1, ORM2

rs17636964

CD

IPMK

rs17645907

T2D

[POMZP3]

rs1842055

CAD

-

rs1868584

CAD, HT, RA, T1D

ROCK2, CGGBP1, [ZNF654]

rs2120273

BD

-

rs2236014

BD

MTRF1L, [FBX05]

rs2515832

RA

MAGEA12, CSAG1, MAGEA2, MAGEA3, TRAG3,

[MAGEA6]

rs2523544

T1D

DHFRP2, DHFRL1, DHFR, PSMA8, [HLA-B], [MSH3], [NSUN3]

rs2617729

CD, T2D

ZNF761, ZNF765, ZNF813, [ZNF331]

rs330201

CAD

MRPL10, [LRRC46], [OSBPL7]

rs3858741

BD, CD, HT

PSPC1, [TUBA3C]

rs4318932

CD

TYW1, TYW1B, [STAG3L4]

rs4453734

CAD, RA

-

rs4473816

RA

[GSPT2]

rs4532803

BD, HT

ELA3A, ELA3B, [HSPC157]

rs4545817

BD

ALG1, FAM86A, [COL6A4P2]

rs4881702

BD

-

rs500192

BD, T1D

TBL1XR1

rs5946541

BD

[BAGE]

rs6427130

RA

XCL1, XCL2

rs6463213

BD, T2D

RBAK, RNF216L, XKR8

rs6744284

BD

UGT1A3 -UGT1A10

rs6945984

RA

CYP3A4, CYP3A7, [CYP3A5]

rs7259082

CAD

ZNF737, M74509, ZNF66

rs7549545

BD

[IER5]

rs7677996

T1D

[UGT2B7]

rs7808342

BD

-

rs940331

T2D

[ZNF735], [ZNF716]

rs9551988

T2D

PSPC1, [TUBA3C]

rs9624808

T1D

LRP5, LRP5L

rs9665670

BD, CAD

[PDSS1]

rs9775226

CD, HT

(40 duplicons)

SNP_A-1797773

BD, CD

VPS35, [ORC6L]

SNP_A-1817967

CD

FAM22A

SNP_A-1858955

RA

GUSBL1, GUSBL2, SMA4, GUSBP1, [RGL4]


Genes in square brackets are outside the duplicons, but a duplicon is at most 30 kb upstream of the gene. Genes for two SNPs having 40 duplicons each are omitted.

Ross BMC Medicine 2011 9:12   doi:10.1186/1741-7015-9-12

Open Data