Table 3

Distributions of genotypes of the MNS16A between the subgroups of casesa with different progression of nasopharyngeal carcinoma (NPC)

NPC stage

LLb n (%)

SL + SSb, n (%)

χ2c

P


Clinical

I

36 (90. 0)

2 (10. 0)

1. 554

0. 21

II

334 (89. 8)

38 (10. 2)

III

212 (90. 2)

23 (9. 8)

IV

143 (93. 5)

10 (6. 5)

Tumor (T)

3. 314

0. 069

T1

151 (91. 5)

14 (8. 5)

T2

356 (89. 9)

40 (10. 1)

T3

139 (89. 7)

16 (10. 3)

T4

79 (96. 3)

3 (3. 7)

Node(N)

0. 667

0. 41

N0

148 (89. 2)

18 (10. 8)

N1

350 (91. 1)

34 (8. 9)

N2

156 (90. 7)

16 (9. 3)

N3

71 (93. 4)

5 (6. 6)

Metastasis(M)

0. 000

1. 00

M0

708 (90. 9)

71 (9. 1)

M1

17 (89. 5)

2 (10. 5)


aOwing to genotyping failure, the actual sample size of the cases was 798.

bL allele, 302 or 333 bp; S allele, 243 or 272 bp.

cComparisons of genotype distributions between the different subgroups were performed using the χ2 test. The degrees of freedom for the clinical, T and N stages is 3, and for the M stage is 1

Zhang et al. BMC Medicine 2011 9:106   doi:10.1186/1741-7015-9-106

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