Table 2

Demographic, physical and medical characteristics of the patients included in the study

Total

DIA without HYP

DIA with HYP

HYP without DIA

Controls


Number

288

22

42

159

65

Age (yr)

54.90 ± 11.68

53.27 ± 12.74

62.17 ± 8.03

56.69 ± 11.08

48.75 ± 11.22

Male sex (%)

62.29

81.81a

66.67a

62.78

53.85

Body mass index (kg/m2)

28.32 ± 4.26

28.71 ± 4.99

30.33 ± 4.86

28.68 ± 3.93

26.82 ± 3.29

Endoglin (ng/mL)

5.04 ± 1.05

5.02 ± 0.98

4.88 ± 1.20

4.39 ± 1.04

5.21 ± 1.10

Basal glycemia (mg/dL)

98.76 ± 30.77

121.22 ± 30.03b,e

132.56 ± 45.52b,e

88.45 ± 11.49

84.47 ± 9.04

HbA1c (%)

5.42 ± 1.05

6.72 ± 1.07b,e

6.80 ± 1.30b,e

5.03 ± 0.45

4.91 ± 0.45

Systolic blood pressure (mmHg)

125.89 ± 12.72

121.34 ± 8.37

126.20 ± 14.21c

127.03 ± 13.94c

123.69 ± 9.52

Diastolic blood pressure (mmHg)

77.05 ± 9.43

73.38 ± 6.08

72.78 ± 9.11a,d

76.82 ± 9.88c

77.65 ± 7.65

Heart rate (beats/min)

71.96 ± 10.56

75.11 ± 11.29

72.51 ± 10.28

71.08 ± 11.06c

72.77 ± 10.31

Leukocytes (103 cells/μL)

6.70 ± 1.95

7.35 ± 2.90a

7.23 ± 1.94a

6.71 ± 1.96a

6.08 ± 1.03

Neutrophils (103 cells/μL)

3.52 ± 1.33

4.06 ± 2.30a

3.76 ± 1.32a

3.52 ± 1.25

3.17 ± 0.93

Lymphocytes (103 cells/μL)

2.41 ± 0.74

2.49 ± 0.61

2.71 ± 0.77

2.42 ± 0.83

2.23 ± 0.52

Monocytes (103 cells/μL)

0.54 ± 0.26

0.56 ± 0.19

0.58 ± 1.18

0.55 ± 0.32

0.47 ± 0.15

Eosinophils (103 cells/μL)

0.21 ± 0.22

0.19 ± 0.10

0.24 ± 0.17

0.23 ± 0.28

0.18 ± 0.11

Basophils (103 cells/μL)

0.04 ± 0.03

0.04 ± 0.02

0.03 ± 0.02

0.04 ± 0.03

0.03 ± 0.03

Smokers (%)

24.92

36.36

16.67

26.81

24.61

High-density lipoproteins (mg/dL)

52.35 ± 12.42

46.27 ± 8.85a,d

47.43 ± 9.74a,d

53.50 ± 12.41

54.13 ± 13.51

Low-density lipoproteins (mg/dL)

125.80 ± 32.67

113.72 ± 27.18a

105.63 ± 25.52a,d

131.43 ± 34.14c

127.13 ± 28.74

Alcohol consumption (U/wk)

11.30 ± 20.33

9.79 ± 15.82

12.70 ± 20.94

12.21 ± 23.45

10.15 ± 18.06

Daily physical activity (%)

34.75

31.82

57.14a

34.78

26.15

FPACD (%)

15.08

9.09

30.95a,c,d

13.77

9.23


Data are expressed as means ± standard deviation or percentage. DIA, patients with diabetes; HbA1c, glycosylated hemoglobin; HYP, patients with hypertension; FPACD, family premature antecedents of cardiovascular disease in first-degree relatives. aStatistically significant differences (P < 0.05) vs. control group; bP < 0.0001 vs. control group; cP < 0.05 vs. DIA without HYP; dP < 0.05 vs. HYP without DIA; eP < 0.0001 vs. HYP without DIA.

Blázquez-Medela et al. BMC Medicine 2010 8:86   doi:10.1186/1741-7015-8-86

Open Data