Table 2

Characteristics of included trials: Short-term trialsa

Trial

Clinical problem

Sample size

(% dropout)

Concealment

Outcome used for meta-analysis

Intervention details

Standard basic care in all groups


Cabrini et al. [41]

Bronchoscopy

48

(0)

Unclear

VAS discomfort after bronchoscopy

N:1

D:20

T:-

Ac:C CA

S:I C 1

Lidocaine as needed

Dundee et al. [43]

Perioperative nausea (minor gynecologic operations)

75

(0)

Unclear

Number of patients vomiting

N:1

D:5

T:-

Ac:C CA

S:I C 1

Premedication 10 mg nalbophine

Fanti et al. [45]

Colonoscopy

30

(0)

Unclear

Satisfaction with sedation using a verbal rating scale

N:1

D:4

T:-

Ac:C EA

S:I C 1

Midazolam 0.02 mg/kg before and during colonoscopyb

Gioia et al. [48]

Sedation during cataract surgery

75

(0)

Unclear

Postoperative anxiety evaluation (VAS)

N:1

D:60

T:-

Ac:C CA

S:I C 1

Topical eye anesthesia (lidocaine 4%)

Karst et al. [50]

Anxiety and tooth extraction

48

(0)

Unclear

VAS anxiety

N:1

D:25

T:-

Ac:C EarA

S:II C 1

Local anesthesia (articaine hydrochloride)

Li et al. [55]

Colonoscopy

36

(0)

Unclear

VAS pain intensity

N:1

D:30

T:-

Ac:C EA

S:I C 1

Routine analgesia and sedation as needed

Rusy et al. [62]

Postoperative nausea after tonsillectomy

120

(0)

Unclear

Incidence of nausea, vomiting, rescue therapy in first 24 hours

N:1

D:20

T:-

Ac:C EA

S:I C 2

Standardized anesthesia, analgesia as needed

Ziaei & Hayipour [69]

Pain reduction and relaxation during labor

90

(unclear)

Unclear

VAS pain after 2 hours

N:1

D:n.i..

T:-

Ac:C CA

S:I C 1

Unclear


aSee Table 1 footnotes for definitions of abbreviations. bClassified as intense cointervention likely to influence the outcome.

Linde et al. BMC Medicine 2010 8:75   doi:10.1186/1741-7015-8-75

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