Table 1

Multiplicity of any category of metastasis^a)

Average No. of organs with metastasis except

for lymph nodes^b)

Groups

Number of mice examined

Total no. of organs with metastasis

Average no. of organs with metastasis/mouse^b)

Lungs

Ovaries

Kidneys

Adrenals

Others

pVec

9

156

16.3 ± 3.3

2.0 ± 0.0

1.9 ± 0.3

1.6 ± 0.5

1.3 ± 0.9

0.0 ± 0.0

pesVEGFR-2

10

106

9.9 ± 4.1**

1.5 ± 0.8

1.8 ± 0.6

1.1 ± 1.0

1.6 ± 0.8

0.1 ± 0.3^c)

pEndo

9

6

0.7 ± 1.1**†

0.0 ± 0.0**†

0.0 ± 0.0 **†

0.0 ± 0.0**†

0.3 ± 0.7 *†

0.1 ±0.3^d)

*P < 0.05; **P < 0.01 as compared with pVec values.

†P < 0.01 as compared with pesVEGFR-2 values.

a) With respect to bilateral organs, one in unilateral metastasis and two in bilateral metastasis were counted.

b) Values are mean ± SD.

c) Metastasis to uterus.

d) Metastasis to subcutis.

Shibata et al. BMC Medicine 2010 8:69   doi:10.1186/1741-7015-8-69