Table 1

Structure of families included in the study.

No. of affecteds

No. of unaffecteds

No. of families with


CAD

CAD before 50 years*

MI †


1

1

164

149

122


1

2

439

235

362


1

>2

49

38

39


2

1

158

46

78


2

2

42

15

23


2

>2

18

6

14


≥ 3

≥1

21

4

11


Total families

891

493

660


Total affecteds

1154

568

802


Total unaffecteds

1545

855

1204


* In this setting, individuals affected after 50 years were considered as unphenotyped

† For this trait coding, individuals free of myocardial infarction (MI) but affected by other forms of coronary artery disease (CAD) were considered unphenotyped.

Brown et al. BMC Medicine 2010 8:5   doi:10.1186/1741-7015-8-5

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