Figure 3.

CpG dinucleotides analyzed within a predicted CpG island in the promoter region of OXTR. Untranslated regions are represented as gray boxes and protein coding exons are white boxes, the site of translation is denoted by a black arrow. Predicted CpG islands are horizontal black bars beneath the gene. The region of interest within the 5' CpG island, MT2 as reported by Kusui et al. [56], is denoted by a dashed line (NCBI36 coordinates). Groups of CpGs sequenced per clone are indicated with brackets. Clear circles with diagonal lines denote untested CpG dinucleotides, filled circles represent region of interest. CpGs of interest are numbered according to translation initiation site of +1. Clear boxes denote CpG dinucleotides that showed no methylation in bisulfite sequencing of subclones; black within boxes denotes methylation of the CpG dinucleotide; F = Father, M = Mother, P = Proband, S = Sibling.

Gregory et al. BMC Medicine 2009 7:62   doi:10.1186/1741-7015-7-62
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