Table 1

Distribution of valvular regurgitation at initial echocardiogram in 4825 women exposed to fenfluramine and/or dexfenfluramine

Ages

<20 (n = 25)

20–29 (n = 386)

30–39 (n = 900)

40–49 (n = 1442)

50–59 (n = 1279)

60–69 (n = 610)

70+ (n = 183)

All ages (n = 4825)


Aortic regurgitation

none (%)

96.0

85.8

75.4

65.4

59.5

59.8

53.6

66.3

trace (%)

4.0

10.1

14.7

17.6

19.9

20.7

29.5

17.8

mild (%)

0

3.1

7.8

11.2

13.4

12.8

11.5

10.7

moderate (%)

0

1.0

2.0

5.1

6.6

5.7

4.9

4.7

severe (%)

0

0

0.11

0.62

0.55

0.98

0.55

0.50

Mitral regurgitation

none (%)

64.0

42.2

36.4

29.8

24.9

22.6

18.6

29.6

trace (%)

32.0

50.8

50.7

54.4

54.3

54.1

48.6

53.0

mild (%)

4.0

4.9

10.3

11.2

13.9

13.6

13.1

11.6

moderate (%)

0

1.8

2.2

4.2

5.5

8.7

15.3

4.9

severe (%)

0

0.26

0.33

0.49

1.5

0.98

4.4

0.91

Tricuspid regurgitation

none (%)

56.0

22.8

24.4

22.8

21.1

18.4

15.3

22.0

trace (%)

28.0

63.5

60.3

62.1

60.0

62.1

60.1

61.1

mild (%)

16.0

11.9

12.6

12.1

12.9

11.5

12.6

12.3

moderate (%)

0

1.8

2.6

2.5

5.2

6.6

10.4

4.0

severe (%)

0

0

0.11

0.55

0.70

1.5

1.6

0.62


Dahl et al. BMC Medicine 2008 6:34   doi:10.1186/1741-7015-6-34

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