Survival prediction accuracy versus distribution of random subsets from the BOAC SNP panel. The 173 SNP profiles were randomly paired 10,000 times, and the accuracy of the SNP prediction was determined, resulting in a distribution of accuracy, centered around 50%. This is compared with survival group prediction accuracy of the full SNP panel (66%) and the subset of SNPs (76%) described in the text. Odds ratios and confidence intervals are given for each. In both cases the p-value for predictive power is less than 0.0001.
Van Ness et al. BMC Medicine 2008 6:26 doi:10.1186/1741-7015-6-26