Table 1

Differentially expressed microRNAs in anaplastic astrocytoma and/or glioblastoma multiforme tumors relative to non-neoplastic brain tissue

Glioblastoma multiforme and anaplastic astrocytoma
Glioblastoma multiforme only
Anaplastic astrocytoma only


Fold change glioblastoma multiforme
Fold change anaplastic astrocytoma
Ref

Fold change glioblastoma multiforme
Ref

Fold change anaplastic astrocytoma
Ref

Down-regulated



Down-regulated


Down-regulated


miR-7
34
13

miR-101
4

miR-125b
153
[22]
miR-31
17
9

miR-128a
27
[22]
miR-126
7

miR-107
14
10

miR-132
7

miR-127
149

miR-124
57
26

miR-133a
17

miR-134
9

miR-124b
45
27

miR-133b
14




miR-129
43
27

miR-149
9

Up-regulated


miR-137
63
66

miR-153
12

miR-296
11

miR-138
27
12
[21]
miR-154*
7

miR-320
5

miR-139
66
34

miR-185
5




miR-187
6
5

miR-29b
6




miR-203
13
4

miR-323
17




miR-218
40
16

miR-328
8








miR-330
18




Up-regulated









miR-10b
35
75
[22]
Up-regulated









miR-21
7
[21,22]







miR-155
8








miR-210
7





P-values for all miRNAs are P < 0.05 for comparisons of miRNA expression in tumors versus glioses; for miRNAs in bold P < 0.01. References indicate high-grade astrocytoma miRNA expression studies in which miRNA has been described previously.

Silber et al. BMC Medicine 2008 6:14   doi:10.1186/1741-7015-6-14