Cumulative incidence curves for dementia in subjects taking statins. Cumulative incidence curves are shown for subjects ≥65 years who were taking each statin. The CV comparator was used as the comparison group. Dark blue line, CV comparator; light blue line, confidence intervals for the CV comparator curve; red line, statin group; pink line, confidence intervals for the statin curves. The first 7 months represent the obligate period for drug treatment, during which subjects were treated and any subjects developing dementia were eliminated from the analysis. (A) Atorvastatin; (B) lovastatin; (C) simvastatin; (D) summary of hazard ratios for each of the statins using model 3.
Wolozin et al. BMC Medicine 2007 5:20 doi:10.1186/1741-7015-5-20