Table 2

Predictive statistics for schizophrenia within those 18 subjects with minor symptoms.

Region

False+, False-

PPV%

NPV%

Likelihood ratio +

Likelihood ratio -

Sensitivity %

Specificity %

Effect size


Right cerebellum

2, 3

71

73

3.13

0.47

63

80

-0.68

Left uncus

3, 5

50

58

1.25

0.89

38

70

-0.09

Left inferior temporal gyrus

3, 3

63

70

2.08

0.54

63

70

-0.55


Statistics for the prediction of the development of schizophrenia within a 10-year period, based on changes in grey matter in the right cerebellum, left uncus and left inferior temporal gyrus (n = 18; only familial high-risk subjects who had transient, partial or isolated psychotic symptoms and had two scans in the first 4 years of the Edinburgh High Risk Study).

+ positive; - negative; NPV, negative predictive value; PPV, positive predictive value.

Job et al. BMC Medicine 2006 4:29   doi:10.1186/1741-7015-4-29

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