Table 5 |
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|
Household contact prophylaxis with antiviral drugs, with or without treatment of the index cases. The interventions are applied in 70% of households in which one member consults a physician. Estimates are cumulative numbers per 100 inhabitants, unless otherwise specified. |
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|
Outcomes |
Prophylaxis (Outbreak, n = 90) |
Prophylaxis + treatment (Outbreak, n = 98) |
||
|
|
||||
|
Mean |
Minimum-Maximum |
Mean |
Minimum-Maximum |
|
|
|
||||
|
Infections |
||||
|
Total |
36.1 |
32.1–40.1 |
34.2 |
30.8–37.4 |
|
Childrena |
61.8 |
57.0–66.2 |
58.5 |
53.1–64.5 |
|
Adultsa |
30.2 |
25.6–35.0 |
28.8 |
24.2–33.4 |
|
Elderlya |
16.8 |
11.2–21.2 |
14.9 |
11.3–18.9 |
|
Physician visits |
23.8 |
21.8–27.0 |
22.2 |
19.6–24.8 |
|
Hospital admissions |
1.18 |
0.70–1.57 |
0.77 |
0.59–0.98 |
|
Deaths |
0.25 |
0.13–0.43 |
0.16 |
0.06–0.28 |
|
Lost workdaysb |
106 |
94–122 |
100 |
85–116 |
|
Treatment units (doses)c |
196 |
179–210 |
393 |
356–435 |
|
|
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|
aPer 100 individuals of a given age bPer 100 working adults cTwo per day of treatment, five days per patient; one per day of prophylaxis, 10 days per person |
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|
Carrat et al. BMC Medicine 2006 4:26 doi:10.1186/1741-7015-4-26 |
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