Flowchart of early treatment discontinuation. Values are the summary of reasons for discontinuation from all 4 studies. Poor Response was based on "Lack of Efficacy." Symptom Worsening was based on "Psychiatric Adverse Events" and a priori protocol defined "Clinical Relapse" (Study 2 only).
Liu-Seifert et al. BMC Medicine 2005 3:21 doi:10.1186/1741-7015-3-21