Figure 7.

Effect of receptor antagonists on THC mediated suppression of KSHV reactivation. BCBL-1 cells were cultured in the presence of 1.25 μg/ml THC (lane THC), 1.25 μg/ml THC plus 5× molar excess of SR141716A and SR144528 for 72 h (lane Anti1+2), or in medium containing equivalent amount of solvent (DMSO). Cells were analyzed for episomal control and linear replicating DNA as described in Figure 1.