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Personalized medicine: risk prediction, targeted therapies and mobile health technology

Daniel F Hayes1, Hugh S Markus2, R David Leslie3 and Eric J Topol4

Author Affiliations

1 University of Michigan School of Public Health, Ann Arbor, Michigan, USA

2 Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK

3 Department of Diabetes, St Bartholomew’s Hospital and Blizard Institute, London, UK

4 Scripps Translational Science Institute, La Jolla, California, USA

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BMC Medicine 2014, 12:37  doi:10.1186/1741-7015-12-37

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Published: 28 February 2014


Personalized medicine is increasingly being employed across many areas of clinical practice, as genes associated with specific diseases are discovered and targeted therapies are developed. Mobile apps are also beginning to be used in medicine with the aim of providing a personalized approach to disease management. In some areas of medicine, patient-tailored risk prediction and treatment are applied routinely in the clinic, whereas in other fields, more work is required to translate scientific advances into individualized treatment. In this forum article, we asked specialists in oncology, neurology, endocrinology and mobile health technology to discuss where we are in terms of personalized medicine, and address their visions for the future and the challenges that remain in their respective fields.

Diabetes; Genetics; Mobile health; Oncology; Personalized medicine; Smartphone; Stroke; Targeted therapy