Table 4

The net reclassification improvement generated by employing different formulas using MDRD as a reference and a cutoff value of 60 mL/min/1.73 m2
Equation used Outcome NRI using a 60 mL/min cutoff P
CKD-EPIcreat Renal death 2% 0.08
Cardiovascular events 0% 0.49
Hospitalization 1% 0.13
No events −2% 0.05
CKD-EPIcyst Renal death 25% <0.01
Cardiovascular events 7% 0.04
Hospitalization 3% 0.30
No events 1% 0.45
CKD-EPIcreatcyst Renal death 18% <0.01
Cardiovascular events 9% 0.03
Hospitalization −2% 0.36
No events 0% 0.49
BIS Renal death −12% 0.01
Cardiovascular events −2% 0.43
Hospitalization −7% 0.07
No events −7% 0.09

Renal death (mortality or renal replacement therapy), severe cardiovascular events, hospitalization or absence of events over a three-year period were used as outcomes. NRI, net reclassification improvement.

Van Pottelbergh et al.

Van Pottelbergh et al. BMC Medicine 2014 12:27   doi:10.1186/1741-7015-12-27

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