Risk of biopsy detectable cancer in a screened population divided by the 25 year risk of death from prostate cancer (solid black line), distant metastasis (solid grey line), and clinical diagnosis of prostate cancer (dashed black line) in an unscreened cohort, by PSA level at age 60. The dashed grey line at a ratio of 1 is included as reference. Risk of biopsy detectable cancer was obtained from the PCPT. The clinical endpoints were obtained from the Malmö cohort. PCPT, Prostate Cancer Prevention Trial; PSA, prostate specific antigen.
Vickers et al. BMC Medicine 2014 12:26 doi:10.1186/1741-7015-12-26