Table 2

Percentage positivity of autoantibodies in celiac children and their parents compared with pediatric controls
P Pediatric controls (N = 88) Celiac disease parents (N = 90) Pediatric celiac disease (N = 70) Optical density cut-off levels Autoantibodies positivity/groups
<0.9 ND. 3.3 4.3 >28 aPS/PT IgA
<0.0001 0***,** ***7.8, ** 45.7*** >28 aPS/PT IgG
0.23> 3.4 9.9 7.1 >28 aPS/PT IgM
0.5> 14.9 11 17.1 >18 Prothrombin IgG
0.07> *12.5 *3.3 11.4 >18 Phospholipid IgG
1> ND. 2.2 1.4 >18 Phospholipid IgM
1> 0 1.1 0 >24 Cardiolipin check

*P <0.05,**P <0.01,***P <0.0001; aPS/PT: antiphosphatidylserine/prothrombin; aPT: antiprothrombin; Ig: immunoglobulin.

Lerner et al.

Lerner et al. BMC Medicine 2013 11:89   doi:10.1186/1741-7015-11-89

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