Additional file 5: Figure S3.

Scheme showing the approach proposed in this study. We present an example for the feature selection step using the artificial neuronal network (ANN) from the characteristics (yellow circle) and two categories (A and B) of images. Green and red squares represent two groups of images. The feature selection step provides the most discriminating characteristics for this comparison (orange circle) and the classification of the images into categories A and B. The blue squares represent new images. ANN classifies them into categories A and B using the selected characteristics. Principal component analysis (PCA) allows quantification of the degree of affection of the images used for the feature selection step, and also for the new images. This quantification is performed using the same selected characteristics.

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Sáez et al. BMC Medicine 2013 11:77   doi:10.1186/1741-7015-11-77