Additional file 1.

Figure S1: Box and whisker plots and bar charts of bedside vital status observations, oxygen saturation and hypoglycemia by arm (fluid arms combined) versus control arm. Table S1: Admission presentation syndromes by randomization arm (FEAST A only). Figure S2 : Hazard ratios and 95% confidence intervals of boluses compared to no bolus for mortality over different levels of oxygen saturation at baseline. Figure S3: Hazard ratios and 95% confidence intervals for boluses compared to no bolus for mortality over different levels of hemoglobin at baseline. Table S2: Terminal clinical events for 297 children that died within 48 hours by baseline presentation. Figure S4a: Cumulative incidence for bolus and no-bolus arms by cardiogenic only, neurological only or respiratory only terminal clinical events. Figure S4b: Cumulative incidence by bolus versus no bolus for combined causes: respiratory and neurological, cardiogenic and neurological, and unknown or other terminal clinical events. Table S3a: Terminal clinical event by 48 hours by randomization arm (bolus versus no bolus) and by whether they were enrolled before or after the protocol amendment. Table S3b: Terminal clinical event by 48 hours by randomization arm (bolus versus no bolus) by malaria status. Table S3c: Terminal clinical events in those with anemia and those without anemia at baseline. Percentages are out of all those enrolled in that arm within the anemia group or non-anemia group (totals are at the top of each column). Table S4a: Mortality at 48 hours with and without persisting features of shock at one hour. Table S4b: Mortality at 48 hours in those with or without hypoxia at baseline.

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Maitland et al. BMC Medicine 2013 11:68   doi:10.1186/1741-7015-11-68