Summary of network analysis. In summary, functional networks in Autism Spectrum Disorder (ASD) are characterized by a high resilience to targeted attacks, and this is consistent for both ASD alone and ASD related to Tuberous Sclerosis Complex (TSC). Functional networks in the TSC group have an altered topology with a decreased clustering coefficient and increased average path length, regardless of a co-morbid diagnosis of ASD. The consistency of our findings is highlighted by the alignment of the data-cloud on the Y-axis (increased resilience for ASD) and on the X-axis (altered network topology for TSC). Groups are displayed with a span of one standard deviation.
Peters et al. BMC Medicine 2013 11:54 doi:10.1186/1741-7015-11-54