Table 2

Sensitivity analyses

Strata of analysis for each outcome

Number of studies included

HR (95% CI); P-value

Heterogeneity


A. Studies with definition for cancer specific mortality included [6,9,19,20,51,52,54,55,58,60]

10

1.49 (1.29 to 1.72); P <0.001

I2:23.4%; P = 0.23

B. Only Stage III/IV colorectal carcinoma studies included [6,24,51,52]

High versus Low: 2

High versus Low: 1.64 (1.34 to 2.00); P <0.001

I2: 0%; P = 0.38

Positive versus Negative: 2

Positive versus Negative: 1.95 (1.32 to 2.87); P = 0.001

I2: 46.7%; P = 0.17

Overall colorectal studies: 4

Overall colorectal studies: 1.70 (1.42 to 2.03); P <0.001

I2: 7.2%; P = 0.36


Tan et al. BMC Medicine 2013 11:52   doi:10.1186/1741-7015-11-52

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