The association of fascin-1 with disease progression in breast, colorectal and lung carcinomas. In the Forest plot, positive versus negative = positive fascin-1 staining versus negative fascin-1 staining. Squares indicate the study-specific effect estimate, with the size proportional to the inverse of the variance (I-V); horizontal lines show study-specific 95% confidence intervals. The diamonds are pooled estimates and their 95% confidence intervals, based on random or fixed effects meta-analysis models. The dashed vertical line is the overall pooled estimate across all included studies and carcinomas. Time-to-disease progression was calculated from the date of surgery to the date of disease progression.
Tan et al. BMC Medicine 2013 11:52 doi:10.1186/1741-7015-11-52