Methylation at the IGF2 and H19 DMRs in the offspring by parental obesity. The graphs represent the mean estimated methylation values of 69 newborns at the IGF2 DMR, and 70 newborns at the H19 DMR. The IGF2 DMR results are based on 14 obese fathers and 25 obese mothers; the results at the H19 DMR are based on 15 obese fathers and 23 obese mothers. For each exposure the differences of the least square means of methylation percentages are shown at each CpG site (bold), as well as standard errors (SE) and P-values. Bars represent standard errors.
Soubry et al. BMC Medicine 2013 11:29 doi:10.1186/1741-7015-11-29