Open Access Highly Accessed Correspondence

Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration

Lisa M McShane1*, Margaret M Cavenagh2, Tracy G Lively3, David A Eberhard4, William L Bigbee5, P Mickey Williams6, Jill P Mesirov7, Mei-Yin C Polley8, Kelly Y Kim9, James V Tricoli10, Jeremy MG Taylor11, Deborah J Shuman12, Richard M Simon13, James H Doroshow12 and Barbara A Conley14

Author Affiliations

1 Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 5W130, MSC 9735, 9609 Medical Center Drive, Bethesda, MD 20892-9735, USA

2 Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 4W432, MSC 9730, 9609 Medical Center Drive, Bethesda, MD 20892, USA

3 Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 4W420, MSC 9730, 9609 Medical Center Drive, Bethesda, MD 20892, USA

4 Department of Pathology and Lineberger Comprehensive Cancer Center, Brinkhous-Bullitt Bldg., Campus Box 7525, University of North Carolina, Chapel Hill, NC 27599, USA

5 Department of Pathology and University of Pittsburgh Cancer Institute, Hillman Cancer Center, UPCI Research Pavilion, Suite 2.32b, 5117 Centre Avenue, Pittsburgh, PA 15213, USA

6 Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Bldg. 320, Room 2, 1050 Boyles Street, Frederick, MD 21702, USA

7 Computational Biology and Bioinformatics, Broad Institute of Massachusetts Institute of Technology and Harvard University, 7 Cambridge Center, Cambridge, MA 02142, USA

8 Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 5W638, 9609 Medical Center Drive, Bethesda, MD 20892, USA

9 Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 4W430, 9609 Medical Center Drive, Bethesda, MD 20892, USA

10 Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 3W526, 9609 Medical Center Drive, Bethesda, MD 20892, USA

11 Department of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA

12 Office of the Director, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 3A44, 31 Center Drive, Bethesda, MD 20892, USA

13 Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 5W110, 9609 Medical Center Drive, Bethesda, MD 20892, USA

14 Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Room 4W426, 9609 Medical Center Drive, Bethesda, MD 20892, USA

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BMC Medicine 2013, 11:220  doi:10.1186/1741-7015-11-220

Published: 17 October 2013

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