Table 2 |
||
| Similarities in oxidative and nitrosative stress (O+NS) pathways and antioxidant levels between encephalomyelitis disseminata/multiple sclerosis (ED/MS) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) | ||
| Oxidative and nitrosative stress (O+NS) | ED/MS | ME/CFS |
| Lipid peroxidation | ✓ | ✓ |
| Increased malondialdehyde | ? | ✓ |
| Elevated peroxynitrite | ✓ | ✓ |
| Nitrated amino acids | ✓ | ✓ |
| Elevated nitric oxide (NO) | ✓ | ✓ |
| Elevated inducible NO synthase (iNOS) | ✓ | ✓ |
| Raised isoprostane levels | ✓ | ✓ |
| Low vitamin E | ✓ | ✓ |
| Reduced levels of glutathione | ✓ | ✓ |
| Low zinc levels | ✓ | ✓ |
| Low coenzyme Q10 concentrations | ? | ✓ |
| O+NS implicated in pathology | ✓ | ✓ |
Morris and Maes
Morris and Maes BMC Medicine 2013 11:205 doi:10.1186/1741-7015-11-205
