Dose–response relationship between alcohol intake(g/day)and depression risk(HR and 95%CI). Restricted cubic spline model. The PREDIMED Study 2003 to 2010. The black line represents the HR and the dashed lines represent the 95% confidence interval. Adjusted for age, smoking, physical activity (MET-min/d), total energy intake (Kcal/day), baseline body mass index (kg/m2), marital status, intervention group, recruiting center, educational level and the number of persons living at home.
Gea et al. BMC Medicine 2013 11:192 doi:10.1186/1741-7015-11-192