Table 4

Hazard ratios (HRs)a and 95% CIs for total mortality in the National Health and Nutrition Examination Survey (NHANES) III (1988 to 2006)
Magnesium intake (mg/day) Serum vitamin D level (ng/ml) P for trend
<20 20 to 31 32 to 39 40
Total mortality
Total Cases 1,274 1,547 558 324
HR (95% CI) 1.00 0.83 (0.74 to 0.94) 0.80 (0.69 to 0.93) 0.79 (0.66 to 0.93) <0.01
<264 Cases 848 786 249 143
HR (95% CI) 1.00 0.89 (0.74 to 1.08) 0.87 (0.69 to 1.08) 0.87 (0.64 to 1.20) 0.23
≥264 Cases 426 761 309 181
HR (95% CI) 1.00 0.77 (0.64 to 0.92) 0.73 (0.58 to 0.93) 0.70 (0.57 to 0.88) <0.01
P for interaction 0.96
Cardiovascular mortality
Total Cases 574 656 253 132
HR (95% CI) 1.00 0.73 (0.62 to 0.86) 0.77 (0.61 to 0.99) 0.73 (0.56 to 0.97) 0.04
<264 Cases 386 346 112 57
HR (95% CI) 1.00 0.83 (0.66 to 1.04) 0.88 (0.61 to 1.28) 0.91 (0.61 to 1.35) 0.45
≥264 Cases 188 310 141 75
HR (95% CI) 1.00 0.59 (0.44 to 0.80) 0.65 (0.44 to 0.95) 0.57 (0.38 to 0.87) <0.05
P for interaction 0.03
Colorectal cancer mortality
Total Cases 32 34 12 8
HR (95% CI) 1.00 0.84 (0.36 to 2.00) 0.80 (0.31 to 2.05) 0.50 (0.15 to 1.73) 0.31
<264 Cases 19 17 3 3
HR (95% CI) 1.00 1.17 (0.39 to 3.56) 0.79 (0.17 to 3.75) 0.85 (0.17 to 4.12) 0.73
≥264 Cases 13 17 9 5
HR (95% CI) 1.00 0.55 (0.16 to 1.85) 0.67 (0.17 to 2.64) 0.28 (0.03 to 2.25) 0.29
P for interaction 0.15

aA Cox’s proportional hazards model was performed with the SURVEYPHREG procedure to estimate odds ratios and 95% confidence intervals. Models were adjusted for age, race, sex, BMI, education attainment, household income, smoking status, alcohol use, physical activity, month of blood collection, intakes of total energy, phosphorus, calcium and magnesium.

Deng et al.

Deng et al. BMC Medicine 2013 11:187   doi:10.1186/1741-7015-11-187

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