Table 3

Correlation between PCT quartiles and mortality adjusted for age, sex, hypertension, diabetes, plasma lipids, renal function, BMI and smoking
Subjects Outcome Number of eventsa Q2 versus Q1 Q3 versus Q1 Q4 versus Q1 P for linear trend
HR (95% CI) HR (95% CI) HR (95% CI)
All subjects All-cause mortality 8.39 1.04 (0.76 to 1.42) 1.22 (0.90 to 1.65) 1.52 (1.13 to 2.06) 0.002**
Cancer mortality 3.88 1.11 (0.70 to 1.74) 1.56 (1.01 to 2.41) 1.78 (1.13 to 2.77) 0.004**
CVD mortality 2.34 1.18 (0.64 to 2.19) 1.01 (0.55 to 1.85) 1.42 (0.79 to 2.57) 0.266
Mortality from causes other than cancer and CVD 2.16 0.90 (0.49 to 1.66) 1.07 (0.59 to1.93) 1.47 (0.82 to 2.63) 0.126
Men All-cause mortality 11.14 0.99 (0.67 to 1.47) 0.96 (0.66 to 1.40) 1.52 (1.07 to 2.16) 0.024*
Cancer mortality 4.92 1.71 (0.95 to 3.07) 1.38 (0.76 to 2.50) 2.37 (1.36 to 4.14) 0.006**
CVD mortality 3.13 0.66 (0.30 to 1.45) 0.69 (0.34 to 1.39) 1.18 (0.62 to 2.25) 0.539
Mortality from causes other than cancer and CVD 3.09 0.71 (0.33 to 1.53) 0.91 (0.46 to 1.78) 1.28 (0.67 to 2.45) 0.428
Women All-cause mortality 6.30 1.29 (0.76 to 2.20) 1.37 (0.79 to 2.38) 1.61 (0.94 to 2.75) 0.081
Cancer mortality 3.13 1.43 (0.72 to 2.83) 1.17 (0.55 to 2.48) 1.57 (0.76 to 3.23) 0.352
CVD mortality 1.74 0.86 (0.27 to 2.97) 1.38 (0.43 to 4.44) 1.47 (0.47 to 4.62) 0.245
Mortality from causes other than cancer and CVD 1.46 1.50 (0.47 to 4.77) 1.93 (0.59 to 6.28) 1.90 (0.58 to 6.16) 0.281

Cox regression analysis adjusted for age, sex, hypertension, diabetes, LDL, HDL, TG, renal function, BMI and smoking. aExpressed per 1,000 person years. BMI, body mass index; CI, confidence interval; CVD, cardiovascular disease; HDL, high-density lipoprotein; HR, hazard ratio; LDL, low-density lipoprotein; PCT, procalcitonin; Q, quartile; TG, triglycerides. *P <0.05, **P <0.01.

Cotoi et al.

Cotoi et al. BMC Medicine 2013 11:180   doi:10.1186/1741-7015-11-180

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