Table 4

Rate ratios for immune-mediated diseases following admission for osteomalacia
Disease O E RR (95% CI) P-value
Addison’s disease 9 1.1 8.1 (3.7 to 15.4) <0.001
Ankylosing spondylitis 5 2.9 1.7 (0.57 to 4.1) 0.33
Asthma (aged 5 to 54) 50 71.9 0.7 (0.5 to 0.9) 0.01
Celiac disease 32 4.9 6.5 (4.4 to 9.2) <0.001
Crohn’s disease 12 7.1 1.7 (0.9 to 3.0) 0.10
Diabetes mellitus (aged 0 to 29) 11 3.8 2.9 (1.5 to 5.2) 0.001
Idiopathic thrombocyt. purpura 5 2.9 1.8 (0.6 to 4.1) 0.33
Myxoedema 143 185.8 0.8 (0.7 to 0.9) 0.002
Pernicious anemia 23 15.1 1.5 (1.0 to 2.3) 0.06
Primary biliary cirrhosis 5 1.9 2.7 (0.9 to 6.3) 0.05
Psoriasis 11 14.6 0.8 (0.4 to 1.4) 0.42
Rheumatoid arthritis 54 49.3 1.1 (0.8 to 1.4) 0.55
Sjogren’s syndrome 8 3.7 2.2 (0.9 to 4.3) 0.04
Thyrotoxicosis 30 20.8 1.4 (1.0 to 2.1) 0.06
Ulcerative colitis 11 10.7 1.0 (0.5 to 1.9) 0.96

O Observed number of cases, E Expected number, RR Rate ratio, 95% CI 95% confidence interval.

Ramagopalan et al.

Ramagopalan et al. BMC Medicine 2013 11:171   doi:10.1186/1741-7015-11-171

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